Diacetone alcohol is widely used as a solvent in various industrial and commercial applications. It is particularly effective in coatings, inks, and adhesives due to its ability to dissolve a broad range of substances while evaporating at a controlled rate. This makes it ideal for use in paints and varnishes, where it helps improve flow and leveling and prevents defects like blistering or orange peel.

It is also used in the formulation of cleaning agents, especially for delicate surfaces, because of its moderate evaporation rate and low toxicity compared to other solvents. In the electronics industry, it serves as a cleaning fluid for circuit boards and components.

Diacetone alcohol is employed in the production of cellulose acetate and other resins. Additionally, it acts as an intermediate in the synthesis of other chemicals, including pharmaceuticals and plasticizers. Its compatibility with water and many organic solvents enhances its utility in multi-component systems.

In cosmetics and personal care products, it functions as a solvent for resins and polymers, aiding in the uniform dispersion of ingredients. It is also used in some nail care products due to its gentle solvency.