Used to treat major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. It helps balance neurotransmitters in the brain that affect mood and pain signals. Commonly prescribed for both emotional and physical symptoms related to these conditions. Also used off-label for stress urinary incontinence and certain types of chronic pain. Effective in improving sleep, energy, and overall well-being in long-term treatment.