2-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazole-3(2H)-thione

97%

Reagent Code: #161831
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CAS Number 178928-70-6

science Other reagents with same CAS 178928-70-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 344.26 g/mol
Formula C₁₄H₁₅Cl₂N₃OS
badge Registry Numbers
MDL Number MFCD08273847
thermostat Physical Properties
Boiling Point 486.7°C at 760 mmHg
inventory_2 Storage & Handling
Storage Store in an inert gas at room temperature

description Product Description

Used as a key intermediate in the synthesis of triazole-based antifungal agents, particularly in the development of agricultural fungicides. Its structure enables strong interaction with fungal enzyme targets, disrupting ergosterol biosynthesis, which is critical for cell membrane integrity. Due to the presence of chlorine-substituted cyclopropyl and phenyl groups, it exhibits enhanced lipophilicity and stability, improving penetration and persistence in plant tissues. It is also explored in medicinal chemistry for potential antimicrobial and antiproliferative activities, serving as a scaffold in drug design for targeting resistant microbial strains.

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Test Parameter Specification
Appearance White to off-white solid
Purity (%) 96.5-100%
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿300.00
inventory 1g
10-20 days ฿720.00
inventory 5g
10-20 days ฿2,150.00
inventory 10g
10-20 days ฿3,760.00
inventory 25g
10-20 days ฿7,380.00
inventory 100g
10-20 days ฿23,100.00
inventory 500g
10-20 days ฿80,880.00

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2-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazole-3(2H)-thione
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Used as a key intermediate in the synthesis of triazole-based antifungal agents, particularly in the development of agricultural fungicides. Its structure enables strong interaction with fungal enzyme targets, disrupting ergosterol biosynthesis, which is critical for cell membrane integrity. Due to the presence of chlorine-substituted cyclopropyl and phenyl groups, it exhibits enhanced lipophilicity and stability, improving penetration and persistence in plant tissues. It is also explored in medicinal ch

Used as a key intermediate in the synthesis of triazole-based antifungal agents, particularly in the development of agricultural fungicides. Its structure enables strong interaction with fungal enzyme targets, disrupting ergosterol biosynthesis, which is critical for cell membrane integrity. Due to the presence of chlorine-substituted cyclopropyl and phenyl groups, it exhibits enhanced lipophilicity and stability, improving penetration and persistence in plant tissues. It is also explored in medicinal chemistry for potential antimicrobial and antiproliferative activities, serving as a scaffold in drug design for targeting resistant microbial strains.

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