Used primarily to reduce pain, inflammation, and stiffness caused by arthritis, including osteoarthritis and rheumatoid arthritis. It is also approved for the management of acute pain, such as after dental surgery or menstrual cramps. Celecoxib helps decrease swelling and discomfort by targeting specific enzymes involved in inflammation. It is considered a preferred option for patients at higher risk of gastrointestinal issues, as it causes fewer stomach and intestinal side effects compared to traditional nonsteroidal anti-inflammatory drugs (NSAIDs). Additionally, it has been studied for its potential in reducing the number of colon polyps in patients with familial adenomatous polyposis, a genetic condition that increases the risk of colorectal cancer.