Colchicine solution
10mM in DMSO
Reagent
Code: #157754
CAS Number
64-86-8
science Other reagents with same CAS 64-86-8
blur_circular Chemical Specifications
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Molecular Information
Weight
399.44 g/mol
Formula
C₂₂H₂₅NO₆
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Registry Numbers
EC Number
200-598-5
MDL Number
MFCD00078484
thermostat
Physical Properties
Melting Point
150-160 °C(dec.)(lit.)
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of gout, colchicine solution helps reduce inflammation and pain during acute gout attacks by inhibiting uric acid crystal-induced neutrophil activation. It is also prescribed for familial Mediterranean fever to prevent recurrent attacks. In cytogenetics, the solution is applied to arrest cell division at metaphase by disrupting microtubule formation, allowing for chromosome analysis. Additionally, it has been used in plant breeding to induce polyploidy, resulting in larger or more robust plant varieties.
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