Carbimazole
10mM in DMSO
Reagent
Code: #157723
CAS Number
22232-54-8
science Other reagents with same CAS 22232-54-8
blur_circular Chemical Specifications
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Molecular Information
Weight
186.23 g/mol
Formula
C₇H₁₀N₂O₂S
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Registry Numbers
MDL Number
MFCD00027421
thermostat
Physical Properties
Melting Point
124 °C
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Storage & Handling
Storage
-20°C
description Product Description
Carbimazole is primarily used in the treatment of hyperthyroidism, a condition where the thyroid gland produces excessive amounts of thyroid hormones. It works by inhibiting the synthesis of these hormones, specifically by blocking the enzyme thyroid peroxidase, which is involved in the production of thyroxine (T4) and triiodothyronine (T3). This helps to normalize hormone levels and alleviate symptoms such as rapid heartbeat, weight loss, tremors, and anxiety.
It is commonly prescribed for patients with Graves’ disease, an autoimmune disorder that is the most frequent cause of hyperthyroidism. Carbimazole is often used as a first-line therapy and can be administered over several months to achieve remission. In some cases, it is used prior to radioiodine treatment or surgery to stabilize thyroid function.
The drug is taken orally and allows for convenient outpatient management. Its use may be associated with dose-dependent side effects, so regular monitoring of thyroid function and blood counts is recommended during treatment.
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