1-(4-Amino-6,7-Dimethoxy-2-Quinazolinyl)-4-[(Tetrahydro-2-Furanyl)Carbonyl]Piperazine Hydrochloride
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Reagent
Code: #136143
CAS Number
70024-40-7
science Other reagents with same CAS 70024-40-7
blur_circular Chemical Specifications
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Molecular Information
Weight
423.89 g/mol
Formula
C₁₉H₂₆ClN₅O₄
thermostat
Physical Properties
Boiling Point
271-274°C
inventory_2
Storage & Handling
Storage
2-8°C
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly those targeting epidermal growth factor receptor (EGFR). It plays a role in the development of anticancer agents, especially for treating non-small cell lung cancer and other solid tumors. Its structure supports high selectivity and potency in inhibiting abnormal kinase activity linked to tumor growth. Also investigated for use in targeted therapies due to its ability to cross cell membranes effectively and enhance drug bioavailability.
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