4-Amino-3-(4-chlorophenyl)butyric Acid, Baclofen
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99%
Reagent
Code: #135248
$product.alias - string(143) "β-(p-chlorophenyl)-γ-aminobutyric acid; barofen; 4-amino-3-(4-chlorophenyl)-butyric acid; chlorophenylbutyric acid; chlorophenyl tyrolic acid"
product.cas - string(9) "1134-47-0"
product.physical_n_chem_properties - string(0) ""
Alias
β-(p-chlorophenyl)-γ-aminobutyric acid; barofen; 4-amino-3-(4-chlorophenyl)-butyric acid; chlorophenylbutyric acid; chlorophenyl tyrolic acid
product.physical_n_chem_properties - string(0) ""
CAS Number
1134-47-0
science Other reagents with same CAS 1134-47-0
blur_circular Chemical Specifications
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Molecular Information
Weight
213.66 g/mol
Formula
C₁₀H₁₂ClNO₂
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Registry Numbers
MDL Number
MFCD00055143
inventory_2
Storage & Handling
Storage
Room temperature, sealed
description Product Description
Used primarily as a muscle relaxant and antispasmodic agent, especially in the treatment of muscle spasticity resulting from conditions like multiple sclerosis, spinal cord injuries, and cerebral palsy. It acts as a GABA-B receptor agonist, reducing the excitability of neurons in the central nervous system, which helps decrease muscle stiffness, spasms, and associated pain. Also used off-label for chronic hiccups, trigeminal neuralgia, and certain types of neuropathic pain. In some cases, it is administered intrathecally via a pump for severe spasticity unresponsive to oral medications.
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