5-Azacytidine
10mM in DMSO
Reagent
Code: #134172
CAS Number
320-67-2
science Other reagents with same CAS 320-67-2
blur_circular Chemical Specifications
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Molecular Information
Weight
244.2 g/mol
Formula
C₈H₁₂N₄O₅
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Registry Numbers
EC Number
206-280-2
MDL Number
MFCD00006539
thermostat
Physical Properties
Melting Point
226-232 °C(dec.)(lit.)
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of myelodysplastic syndromes (MDS), a group of blood and bone marrow disorders. It works by inhibiting DNA methylation, which can reactivate tumor suppressor genes silenced in cancer cells. This epigenetic modulation helps restore normal cell function and control abnormal blood cell production. Also investigated for use in acute myeloid leukemia (AML) and other hematologic malignancies. In research, it serves as a tool to study DNA methylation and cellular differentiation.
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