Used in the treatment of HIV infection as part of antiretroviral therapy. It works by inhibiting the reverse transcriptase enzyme, preventing the virus from replicating in human cells. Commonly prescribed in combination with other antiretroviral drugs to reduce viral load and improve immune function. Often used in both adult and pediatric patients, especially in formulations suitable for children. Requires HLA-B*5701 genetic screening before use to avoid severe hypersensitivity reactions.