Adapalene is primarily used in dermatology for the treatment of acne vulgaris. It works by regulating the growth of skin cells and preventing the formation of comedones (blackheads and whiteheads). Its anti-inflammatory properties make it effective in reducing papules and pustules associated with mild to moderate acne. It is commonly formulated in topical gels or creams at concentrations suitable for daily use. Due to its stability and compatibility with other acne treatments like benzoyl peroxide and antibiotics, it is often included in combination therapies. Adapalene is also known to improve skin texture and reduce post-inflammatory hyperpigmentation, making it beneficial for patients with acne-related skin discoloration. It is considered safe for long-term use and is widely prescribed for both adolescent and adult acne.