Used primarily as a reference standard in analytical testing, this solution ensures accurate quantification and quality control of ketoconazole in pharmaceutical formulations. It is essential in high-performance liquid chromatography (HPLC) and other analytical methods to validate the concentration, purity, and stability of ketoconazole in drugs and topical products. Also employed in research settings to develop and optimize assays for antifungal activity, pharmacokinetics, and formulation analysis. Its precise concentration supports compliance with regulatory standards in drug manufacturing and testing laboratories.