Used primarily as a reference standard in analytical testing, this solution ensures accurate quantification and quality control of ketoconazole in pharmaceutical formulations. It is essential in HPLC and other chromatographic methods to validate assay performance, confirm potency, and detect impurities in antifungal drug products. Also employed in research settings to study drug stability, dissolution profiles, and formulation development. Its precise concentration supports compliance with regulatory requirements in pharmaceutical manufacturing and quality assurance.