Adapalene is widely used in dermatology for the treatment of acne vulgaris. It is a topical retinoid that helps to normalize skin cell turnover, preventing the formation of comedones (blackheads and whiteheads). By reducing inflammation and unclogging pores, it effectively treats both inflammatory and non-inflammatory acne lesions. It is often prescribed for mild to moderate acne and is suitable for long-term use due to its favorable safety profile. Additionally, adapalene is sometimes used off-label to improve the appearance of fine wrinkles, hyperpigmentation, and other signs of photoaging. Its gentle formulation makes it suitable for use in combination with other acne treatments, such as benzoyl peroxide or antibiotics, for enhanced efficacy.