Colchicine is primarily used in the treatment of gout, a condition characterized by severe pain, redness, and swelling in joints due to the accumulation of uric acid crystals. It works by reducing inflammation and preventing the formation of these crystals, providing relief from acute gout attacks. Additionally, it is employed in the management of familial Mediterranean fever (FMF), a genetic disorder that causes recurrent fevers and inflammation in the abdomen, lungs, and joints. Colchicine helps in preventing FMF episodes and reducing the risk of complications such as amyloidosis. In agriculture, colchicine is used as a chemical mutagen to induce polyploidy in plants, facilitating the development of new plant varieties with altered characteristics. Beyond these applications, it has been explored in research for its potential anti-cancer properties, particularly in inhibiting cell division, though its application in oncology remains under investigation.