Duloxetine hydrochloride is the hydrochloride salt of duloxetine, a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used as an active pharmaceutical ingredient (API) in medications for treating major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic peripheral neuropathy, fibromyalgia, chronic musculoskeletal pain (including osteoarthritis), and stress urinary incontinence. It modulates neurotransmitter levels in the brain to alleviate symptoms of depression, anxiety, and chronic pain. This high-purity compound (≥98% by HPLC) is supplied as a white to beige powder and is intended for pharmaceutical manufacturing, research, and development purposes.