Nona-arginine is widely used in biomedical research and drug delivery due to its ability to enhance cellular uptake. It is particularly effective in delivering therapeutic molecules, such as drugs, proteins, and nucleic acids, into cells by facilitating penetration through cell membranes, leveraging its positively charged peptide structure that binds well to negatively charged cell membranes. This property makes it valuable in gene therapy, where it helps transport DNA or RNA into target cells for genetic modification, including applications in treating genetic diseases. Additionally, nona-arginine is employed in cancer research to deliver anticancer agents directly into tumor cells, improving treatment efficacy. It is also studied in vaccine development, particularly for delivering immune-stimulating agents into the body. Furthermore, nona-arginine finds applications in cosmetics to enhance the absorption of active ingredients through the skin. Its role in improving the bioavailability of poorly permeable drugs further highlights its significance in pharmaceutical development.