4-(((7-Oxo-6,7-dihydro-8H-thiazolo[5,4-e]indol-8-ylidene)methyl)amino)-N-(pyridin-2-yl)benzenesulfonamide

98%

Reagent Code: #220964
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CAS Number 222036-17-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 449.5 g/mol
Formula C₂₁H₁₅N₅O₃S₂
badge Registry Numbers
MDL Number MFCD03452930
inventory_2 Storage & Handling
Density 1.635±0.06 g/cm3(Predicted)
Storage -20°C, Sealed, Dry

description Product Description

Used in research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK2 and CDK9, making it a valuable tool in studies related to cell cycle regulation and transcription in cancer biology. It shows promise in preclinical models for suppressing tumor growth by inducing cell cycle arrest and apoptosis. Its structure allows for strong binding to the ATP-binding site of CDKs, enhancing its inhibitory activity. Also employed in biochemical assays to probe kinase signaling pathways and assess the therapeutic potential of CDK inhibition in diseases like leukemia and solid tumors.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1mg
10-20 days ฿8,380.00
inventory 5mg
10-20 days ฿29,340.00
inventory 10mg
10-20 days ฿44,000.00

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