5-((3-(4-Fluorophenyl)-1H-pyrazol-4-yl)methylene)-2-imino-3-(thiazol-2-yl)thiazolidin-4-one
98%
Reagent
Code: #186584
CAS Number
351062-08-3
science Other reagents with same CAS 351062-08-3
blur_circular Chemical Specifications
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Molecular Information
Weight
371.41 g/mol
Formula
C₁₆H₁₀FN₅OS₂
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Registry Numbers
MDL Number
MFCD02334728
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used in pharmaceutical research as a key scaffold in the development of kinase inhibitors, particularly for targeting cancer-related enzymes such as cyclin-dependent kinases (CDKs). Its structure supports strong binding to ATP sites in kinases, making it valuable in designing compounds that regulate cell proliferation. Also investigated for anti-inflammatory and antimicrobial properties due to its heterocyclic core and fluorinated aromatic group. Commonly employed in structure-activity relationship (SAR) studies to optimize potency and selectivity in drug candidates.
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