8-Chloro-2-Phenyl-3-((1S)-1-((9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purin-6-Yl)Amino)Ethyl)Isoquinolin-1(2H)-One
98%
Reagent
Code: #165337
CAS Number
1350643-73-0
science Other reagents with same CAS 1350643-73-0
blur_circular Chemical Specifications
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Molecular Information
Weight
500.98 g/mol
Formula
C₂₇H₂₅ClN₆O₂
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Storage & Handling
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK9. It is employed in studies targeting transcription regulation in cancer cells, where CDK9 plays a key role in promoting cell survival and proliferation. The compound shows promise in preclinical models for treating hematological malignancies and solid tumors due to its ability to suppress oncogenic transcription. Its structure allows for high binding affinity and improved pharmacokinetic properties, making it a valuable tool compound in kinase inhibitor development and a potential candidate for further optimization in anticancer drug discovery.
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