Q-VD-Oph is a potent pan-caspase inhibitor widely used in research to prevent apoptosis, or programmed cell death, in various experimental models. It is particularly effective in improving cell survival in situations where caspase activation leads to cell degradation, such as in primary cell cultures, organotypic slices, and stem cell differentiation protocols. Due to its high permeability and low toxicity, Q-VD-Oph is preferred over other caspase inhibitors like Z-VAD-FMK in long-term studies. It is commonly applied in neuroscience research to protect neurons in models of neurodegeneration, ischemia, and traumatic injury. It is also used in studies of inflammation, where apoptosis contributes to tissue damage, and in improving the yield of viable cells during isolation procedures. Its stability in aqueous solutions and ability to function at lower concentrations make it suitable for both in vitro and in vivo applications.