PF-670462
≥98%(HPLC)
blur_circular Chemical Specifications
description Product Description
PF-670462 is primarily used in research and development within the field of neuroscience. It acts as a selective inhibitor of casein kinase 1 (CK1) isoforms, particularly CK1δ and CK1ε. This property makes it a valuable tool for studying the role of these enzymes in circadian rhythms, as CK1δ and CK1ε are known to regulate the stability and function of key clock proteins. Researchers utilize PF-670462 to investigate its effects on sleep-wake cycles, metabolic processes, and other biological rhythms. Additionally, it has potential applications in exploring therapeutic strategies for disorders linked to circadian rhythm disruptions, such as sleep disorders, mood disorders, and neurodegenerative diseases. Its ability to modulate CK1 activity also makes it relevant in cancer research, where CK1 isoforms are implicated in tumor progression and cell cycle regulation.
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