AVE 0991 is primarily used in research settings to study its effects on the cardiovascular system. It is known to act as an agonist of the Mas receptor, which plays a role in the protective pathways of the renin-angiotensin system. Researchers utilize it to investigate its potential in reducing hypertension, improving vascular function, and mitigating organ damage associated with cardiovascular diseases. Its application is also explored in studies related to inflammation, fibrosis, and oxidative stress, as it may offer protective benefits in these conditions. Additionally, AVE 0991 is used in preclinical models to understand its therapeutic potential in heart failure and other related disorders.