Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate
97%
science Other reagents with same CAS 144690-33-5
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description Product Description
This compound is primarily utilized in the pharmaceutical industry as an intermediate in the synthesis of active pharmaceutical ingredients (APIs). It plays a crucial role in the development of drugs targeting cardiovascular diseases, particularly those acting as angiotensin II receptor antagonists. These drugs are widely used to manage hypertension and heart failure by blocking the effects of angiotensin II, a hormone that constricts blood vessels. The compound’s structure, featuring a tetrazole moiety and imidazole ring, is essential for its binding affinity and specificity to the target receptors. Additionally, its trityl-protected tetrazole group ensures stability during synthetic processes, making it a valuable component in complex multi-step drug synthesis.
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| Test Parameter | Specification |
|---|---|
| Appearance | White to Off-White Solid |
| Purity (%) | 96.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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