(S,E)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxyhept-2-enoic acid
98%
Reagent
Code: #232808
CAS Number
1105067-93-3
science Other reagents with same CAS 1105067-93-3
blur_circular Chemical Specifications
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Molecular Information
Weight
540.62 g/mol
Formula
C₃₃H₃₃FN₂O₄
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Registry Numbers
MDL Number
MFCD34469881
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily as an active pharmaceutical ingredient in the treatment of hyperlipidemia, particularly for lowering low-density lipoprotein (LDL) cholesterol and reducing cardiovascular risk. It functions as a potent inhibitor of HMG-CoA reductase, the enzyme responsible for a key step in cholesterol biosynthesis in the liver. This inhibition leads to upregulation of LDL receptors, enhancing clearance of LDL from the bloodstream. Commonly prescribed for patients with elevated cholesterol levels, especially those at risk for atherosclerotic cardiovascular disease. Also studied for potential anti-inflammatory and plaque-stabilizing effects in vascular walls. Administered orally, typically once daily, and often part of long-term management strategies in conjunction with diet and lifestyle changes.
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