(R)-(2-Methyloxiran-2-yl)methyl 4-nitrobenzoate

98%

Reagent Code: #231021
label
Alias (2R)-(-)-2-methylcyclopropoxy-4-nitrophenic acid; (2R)-(-)-2-methyl-4-nitrobenzoic acid glycidyl ester
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CAS Number 106268-96-6

science Other reagents with same CAS 106268-96-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 237.21 g/mol
Formula C₁₁H₁₁NO₅
badge Registry Numbers
MDL Number MFCD00012315
thermostat Physical Properties
Melting Point 87-89 °C(lit.)
Boiling Point 382.6 ºC at 760 mmHg
inventory_2 Storage & Handling
Density 1.321 g/cm3
Storage 2-8°C, dry

description Product Description

Used as a chiral epoxide intermediate in organic synthesis, particularly in the preparation of beta-blockers and other pharmaceuticals. Its activated ester group allows for selective nucleophilic attack on the epoxide, enabling controlled ring-opening reactions. The 4-nitrobenzoate moiety also serves as a temporary protecting group for the primary alcohol, which can be removed under mild conditions using weak nucleophiles such as hydroxide ion or ammonia, making it suitable for multi-step syntheses. The compound is valuable in asymmetric synthesis due to its stereochemical integrity, facilitating the construction of complex molecules with high enantiomeric purity. Commonly employed in the development of cardioselective drugs and as a building block in medicinal chemistry research.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿550.00
inventory 1g
10-20 days ฿830.00
inventory 5g
10-20 days ฿3,480.00
inventory 25g
10-20 days ฿13,780.00

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(R)-(2-Methyloxiran-2-yl)methyl 4-nitrobenzoate
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Used as a chiral epoxide intermediate in organic synthesis, particularly in the preparation of beta-blockers and other pharmaceuticals. Its activated ester group allows for selective nucleophilic attack on the epoxide, enabling controlled ring-opening reactions. The 4-nitrobenzoate moiety also serves as a temporary protecting group for the primary alcohol, which can be removed under mild conditions using weak nucleophiles such as hydroxide ion or ammonia, making it suitable for multi-step syntheses. The

Used as a chiral epoxide intermediate in organic synthesis, particularly in the preparation of beta-blockers and other pharmaceuticals. Its activated ester group allows for selective nucleophilic attack on the epoxide, enabling controlled ring-opening reactions. The 4-nitrobenzoate moiety also serves as a temporary protecting group for the primary alcohol, which can be removed under mild conditions using weak nucleophiles such as hydroxide ion or ammonia, making it suitable for multi-step syntheses. The compound is valuable in asymmetric synthesis due to its stereochemical integrity, facilitating the construction of complex molecules with high enantiomeric purity. Commonly employed in the development of cardioselective drugs and as a building block in medicinal chemistry research.

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