(3R,4S)-1-(4-Fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

98%

Reagent Code: #229002
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CAS Number 163380-16-3

science Other reagents with same CAS 163380-16-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 409.43 g/mol
Formula C₂₄H₂₁F₂NO₃
badge Registry Numbers
MDL Number MFCD00937873
thermostat Physical Properties
Melting Point 129.5-132.5 °C
Boiling Point 654.9±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.334±0.06 g/cm3(Predicted)
Storage 2-8°C, Sealed

description Product Description

Widely used in the pharmaceutical industry as a key intermediate in the synthesis of statin-class drugs, particularly for cholesterol-lowering medications. It plays a critical role in constructing the core structure of certain HMG-CoA reductase inhibitors, which are essential for managing hyperlipidemia and reducing cardiovascular risk. Due to its chiral centers and specific stereochemistry, it enables high selectivity and potency in the final drug product. Its derivatives contribute to improved metabolic stability and bioavailability in therapeutic agents. Commonly involved in multi-step syntheses where functional groups like the hydroxyl and fluorophenyl moieties are further modified to achieve the active pharmaceutical ingredient.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿42,240.00

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(3R,4S)-1-(4-Fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
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Widely used in the pharmaceutical industry as a key intermediate in the synthesis of statin-class drugs, particularly for cholesterol-lowering medications. It plays a critical role in constructing the core structure of certain HMG-CoA reductase inhibitors, which are essential for managing hyperlipidemia and reducing cardiovascular risk. Due to its chiral centers and specific stereochemistry, it enables high selectivity and potency in the final drug product. Its derivatives contribute to improved metaboli

Widely used in the pharmaceutical industry as a key intermediate in the synthesis of statin-class drugs, particularly for cholesterol-lowering medications. It plays a critical role in constructing the core structure of certain HMG-CoA reductase inhibitors, which are essential for managing hyperlipidemia and reducing cardiovascular risk. Due to its chiral centers and specific stereochemistry, it enables high selectivity and potency in the final drug product. Its derivatives contribute to improved metabolic stability and bioavailability in therapeutic agents. Commonly involved in multi-step syntheses where functional groups like the hydroxyl and fluorophenyl moieties are further modified to achieve the active pharmaceutical ingredient.

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