(R,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3-hydroxy-5-oxohept-6-enoic acid
97%
Reagent
Code: #228985
CAS Number
1422619-13-3
science Other reagents with same CAS 1422619-13-3
blur_circular Chemical Specifications
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Molecular Information
Weight
479.52 g/mol
Formula
C₂₂H₂₆FN₃O₆S
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Registry Numbers
MDL Number
MFCD18382415
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Storage & Handling
Storage
-20°C
description Product Description
Used in the treatment of hyperlipidemia, particularly to lower low-density lipoprotein (LDL) cholesterol and reduce the risk of cardiovascular diseases. It functions as a potent inhibitor of HMG-CoA reductase, the enzyme responsible for cholesterol synthesis in the liver. This inhibition leads to upregulation of LDL receptors on hepatocytes, increasing clearance of LDL from the bloodstream. Commonly prescribed for patients with elevated cholesterol levels, especially when lifestyle modifications are insufficient. Also shows benefits in stabilizing atherosclerotic plaques and reducing inflammation in blood vessels.
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