Omecamtiv mecarbil
10mM in DMSO
Reagent
Code: #221235
CAS Number
873697-71-3
science Other reagents with same CAS 873697-71-3
blur_circular Chemical Specifications
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Molecular Information
Weight
401.43 g/mol
Formula
C₂₀H₂₄FN₅O₃
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Storage & Handling
Storage
-20°C
description Product Description
Used in the treatment of chronic heart failure, this compound functions as a cardiac myosin activator. It enhances myocardial contractility by increasing the duration of systolic ejection time, improving the heart's pumping efficiency without raising intracellular calcium levels or myocardial oxygen consumption significantly. It is particularly studied for patients with reduced ejection fraction, offering a novel mechanism to support heart function in advanced cardiac conditions. Clinical development focuses on reducing cardiovascular death and heart failure events in long-term management.
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