(3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone

≥98%(HPLC)

Reagent Code: #215450
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CAS Number 1881244-28-5

science Other reagents with same CAS 1881244-28-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 463.46 g/mol
Formula C₂₄H₂₂FN₅O₄
thermostat Physical Properties
Boiling Point 660.5±65.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.54±0.1 g/cm3(Predicted)
Storage -20°C, Sealed, Dry

description Product Description

This compound is used primarily in the development of pharmaceutical agents as a key intermediate in the synthesis of potent cholesterol-lowering drugs, such as those in the statin class. The final drugs synthesized using this intermediate inhibit HMG-CoA reductase, an enzyme central to cholesterol biosynthesis in the liver. Due to its stereochemistry and structural specificity, it contributes to the drug’s selective binding to the enzyme, enhancing efficacy and reducing side effects. Its application is valuable in creating medications for managing hypercholesterolemia and reducing cardiovascular risk. The fluorophenyl and triazole moieties provide metabolic stability and improved bioavailability, making the resulting drugs suitable for oral dosage forms.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿12,450.00
inventory 25mg
10-20 days ฿45,310.00

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(3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone
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This compound is used primarily in the development of pharmaceutical agents as a key intermediate in the synthesis of potent cholesterol-lowering drugs, such as those in the statin class. The final drugs synthesized using this intermediate inhibit HMG-CoA reductase, an enzyme central to cholesterol biosynthesis in the liver. Due to its stereochemistry and structural specificity, it contributes to the drug’s selective binding to the enzyme, enhancing efficacy and reducing side effects. Its application is

This compound is used primarily in the development of pharmaceutical agents as a key intermediate in the synthesis of potent cholesterol-lowering drugs, such as those in the statin class. The final drugs synthesized using this intermediate inhibit HMG-CoA reductase, an enzyme central to cholesterol biosynthesis in the liver. Due to its stereochemistry and structural specificity, it contributes to the drug’s selective binding to the enzyme, enhancing efficacy and reducing side effects. Its application is valuable in creating medications for managing hypercholesterolemia and reducing cardiovascular risk. The fluorophenyl and triazole moieties provide metabolic stability and improved bioavailability, making the resulting drugs suitable for oral dosage forms.

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