(3R,4S)-rel-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H)-1,2,4-triazol-1-carbonyl)-4-piperidinyl]-2-azetidinone
≥98%(HPLC)
science Other reagents with same CAS 1881244-28-5
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description Product Description
This compound is used primarily in the development of pharmaceutical agents as a key intermediate in the synthesis of potent cholesterol-lowering drugs, such as those in the statin class. The final drugs synthesized using this intermediate inhibit HMG-CoA reductase, an enzyme central to cholesterol biosynthesis in the liver. Due to its stereochemistry and structural specificity, it contributes to the drug’s selective binding to the enzyme, enhancing efficacy and reducing side effects. Its application is valuable in creating medications for managing hypercholesterolemia and reducing cardiovascular risk. The fluorophenyl and triazole moieties provide metabolic stability and improved bioavailability, making the resulting drugs suitable for oral dosage forms.
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