Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate
98%
Reagent
Code: #183479
Alias
(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid ethyl ester
CAS Number
172336-32-2
science Other reagents with same CAS 172336-32-2
blur_circular Chemical Specifications
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Molecular Information
Weight
449.51 g/mol
Formula
C₂₇H₂₈FNO₄
thermostat
Physical Properties
Boiling Point
670.4±55.0℃(Predicted)
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Storage & Handling
Density
1.271g/ml
Storage
Room temperature
description Product Description
Used in research as a key intermediate for synthesizing biologically active compounds, particularly in the development of potential cholesterol-lowering agents. Its structure supports activity as an inhibitor of HMG-CoA reductase, an enzyme targeted by statin-class drugs. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and metabolic stability in new drug candidates. Also utilized in preclinical studies to evaluate pharmacokinetic properties and efficacy in models of hyperlipidemia.
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