Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate

98%

Reagent Code: #183479
label
Alias (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid ethyl ester
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CAS Number 172336-32-2

science Other reagents with same CAS 172336-32-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 449.51 g/mol
Formula C₂₇H₂₈FNO₄
thermostat Physical Properties
Boiling Point 670.4±55.0℃(Predicted)
inventory_2 Storage & Handling
Density 1.271g/ml
Storage Room temperature

description Product Description

Used in research as a key intermediate for synthesizing biologically active compounds, particularly in the development of potential cholesterol-lowering agents. Its structure supports activity as an inhibitor of HMG-CoA reductase, an enzyme targeted by statin-class drugs. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and metabolic stability in new drug candidates. Also utilized in preclinical studies to evaluate pharmacokinetic properties and efficacy in models of hyperlipidemia.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿2,680.00
inventory 5g
10-20 days ฿9,300.00

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Ethyl (E)-3,5-dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-hept-6-enoate
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Used in research as a key intermediate for synthesizing biologically active compounds, particularly in the development of potential cholesterol-lowering agents. Its structure supports activity as an inhibitor of HMG-CoA reductase, an enzyme targeted by statin-class drugs. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and metabolic stability in new drug candidates. Also utilized in preclinical studies to evaluate pharmacokinetic properties and efficacy in models of hyperlipidemia.
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