Ethyl 2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-1h-benzo[d]imidazole-5-carboxylate
99%
science Other reagents with same CAS 1408238-41-4
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description Product Description
This compound is a key intermediate in the synthesis of Dabigatran etexilate, a direct thrombin inhibitor used as an anticoagulant for preventing stroke and systemic embolism in patients with atrial fibrillation and for treating deep vein thrombosis. The benzimidazole core with the 4-carbamimidoylphenyl aminomethyl substituent enables specific binding to the thrombin active site, inhibiting fibrin formation. The ethyl ester group enhances solubility during synthesis and serves as a prodrug moiety. It is employed in pharmaceutical research and manufacturing for cardiovascular therapies, with favorable pharmacokinetic properties supporting oral administration.
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