Ethyl 2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-1h-benzo[d]imidazole-5-carboxylate

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Reagent Code: #181016
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CAS Number 1408238-41-4

science Other reagents with same CAS 1408238-41-4

blur_circular Chemical Specifications

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Weight 351.4 g/mol
Formula C₁₉H₂₁N₅O₂
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

This compound is a key intermediate in the synthesis of Dabigatran etexilate, a direct thrombin inhibitor used as an anticoagulant for preventing stroke and systemic embolism in patients with atrial fibrillation and for treating deep vein thrombosis. The benzimidazole core with the 4-carbamimidoylphenyl aminomethyl substituent enables specific binding to the thrombin active site, inhibiting fibrin formation. The ethyl ester group enhances solubility during synthesis and serves as a prodrug moiety. It is employed in pharmaceutical research and manufacturing for cardiovascular therapies, with favorable pharmacokinetic properties supporting oral administration.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿20,000.00

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Ethyl 2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-1h-benzo[d]imidazole-5-carboxylate
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This compound is a key intermediate in the synthesis of Dabigatran etexilate, a direct thrombin inhibitor used as an anticoagulant for preventing stroke and systemic embolism in patients with atrial fibrillation and for treating deep vein thrombosis. The benzimidazole core with the 4-carbamimidoylphenyl aminomethyl substituent enables specific binding to the thrombin active site, inhibiting fibrin formation. The ethyl ester group enhances solubility during synthesis and serves as a prodrug moiety. It is

This compound is a key intermediate in the synthesis of Dabigatran etexilate, a direct thrombin inhibitor used as an anticoagulant for preventing stroke and systemic embolism in patients with atrial fibrillation and for treating deep vein thrombosis. The benzimidazole core with the 4-carbamimidoylphenyl aminomethyl substituent enables specific binding to the thrombin active site, inhibiting fibrin formation. The ethyl ester group enhances solubility during synthesis and serves as a prodrug moiety. It is employed in pharmaceutical research and manufacturing for cardiovascular therapies, with favorable pharmacokinetic properties supporting oral administration.

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