Zatebradine hydrochloride is primarily used in cardiovascular research to study heart rate regulation. It acts as a specific bradycardic agent, slowing down the heart rate without significantly affecting other cardiac functions. This makes it a valuable tool in experimental studies focused on understanding the mechanisms of heart rate control and the development of treatments for conditions like tachycardia. Additionally, it has been explored for its potential therapeutic applications in managing heart rhythm disorders, particularly in cases where reducing heart rate is beneficial without compromising cardiac output. Its precise action on the sinoatrial node allows researchers to investigate the physiological and pathological aspects of heart rate modulation.