This chemical is primarily used as a reagent in organic synthesis, particularly for the activation of carboxylic acids. It facilitates the conversion of carboxylic acids into more reactive intermediates, such as acylating agents, which are essential for forming amides, esters, and other derivatives. Its trifluoroacetyl group enhances reactivity, making it valuable in peptide synthesis and other complex molecular constructions. Additionally, it is employed in the preparation of pharmaceuticals and fine chemicals where precise and efficient acylation reactions are required. Its stability and effectiveness in anhydrous conditions make it a preferred choice in specialized chemical processes.