()-Potassium Ds-threo-isocitrate monobasic is primarily used in biochemical and medical research due to its role in the tricarboxylic acid (TCA) cycle, a critical metabolic pathway in cellular energy production. It serves as a substrate or intermediate in studies related to cellular respiration, enzyme kinetics, and metabolic regulation. This compound is also utilized in the formulation of cell culture media, where it supports the growth and maintenance of cells by providing essential metabolic intermediates. Additionally, it finds application in diagnostic assays and as a reagent in the study of metabolic disorders, helping researchers understand and model diseases related to mitochondrial dysfunction or energy metabolism.