Monodisperse carboxy silica microspheres are widely used in biomedical research for drug delivery systems due to their uniform size and surface functionalization. They serve as excellent carriers for targeted drug release, enhancing the efficiency and specificity of therapeutic agents. In diagnostics, these microspheres are employed in immunoassays and biosensors, where their carboxyl groups facilitate the conjugation of biomolecules like antibodies or DNA probes. They are also utilized in chromatography as stationary phases, providing high-resolution separation of complex mixtures. Additionally, their application in material science includes their use as templates for synthesizing nanostructured materials or coatings with tailored properties. Their biocompatibility and surface reactivity make them versatile tools in various scientific and industrial fields.