Monodisperse carboxy silica microspheres are widely used in biomedical research for drug delivery systems due to their uniform size and surface functionalization. They serve as excellent carriers for targeted drug release, enhancing the efficiency and precision of therapeutic agents. In diagnostics, these microspheres are employed in immunoassays and biosensors, where their carboxyl groups facilitate the conjugation of biomolecules like antibodies or DNA probes. They are also utilized in chromatography as stationary phases, improving separation efficiency and resolution in analytical processes. Additionally, their application extends to material science, where they act as building blocks for creating structured materials with tailored properties.