Monodisperse carboxy silica microspheres are widely used in biomedical research for drug delivery systems due to their uniform size and functional carboxyl groups, which allow for easy surface modification and attachment of therapeutic agents. In diagnostics, they serve as carriers for biomarkers in immunoassays, enhancing detection sensitivity and accuracy. These microspheres are also employed in chromatography as stationary phases, providing high-resolution separation of complex mixtures. Additionally, they are utilized in material science for creating advanced coatings and composites, improving mechanical and optical properties. Their biocompatibility and stability make them suitable for use in tissue engineering scaffolds, promoting cell growth and regeneration.