Tetraethyl orthocarbonate is primarily used as a reagent in organic synthesis, particularly in the preparation of acetals and ketals, which are valuable intermediates in various chemical reactions. It is also employed in the protection of carbonyl groups during complex synthetic processes, ensuring selective transformations without unwanted side reactions. Additionally, this compound finds application in the production of specialty chemicals, including pharmaceuticals and agrochemicals, where its ability to act as a dehydrating agent or a source of ethoxy groups is utilized. In the field of materials science, it is used in the synthesis of polymers and coatings, contributing to the development of advanced materials with specific properties.