N-6-Methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]acetamide

98%

Reagent Code: #217976
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CAS Number 147200-03-1

science Other reagents with same CAS 147200-03-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 338.424 g/mol
Formula C₁₀H₁₄N₂O₅S₃
badge Registry Numbers
MDL Number MFCD12407171
inventory_2 Storage & Handling
Density 1.62g/ml
Storage 2-8℃, inert gas, avoiding light

description Product Description

This compound is a key synthetic intermediate used in the production of dorzolamide, a sulfonamide-based carbonic anhydrase inhibitor. Dorzolamide is primarily employed as a topical ophthalmic agent for the treatment of glaucoma and ocular hypertension, where it reduces intraocular pressure by decreasing the formation of aqueous humor. The intermediate's structure, featuring a protected acetamide group at the 4-position of the thieno[2,3-b]thiopyran core and a sulfamoyl substituent, facilitates the enzymatic inhibition mechanism in the final drug. It is not intended for direct therapeutic use but supports the manufacturing of specialized pharmaceutical formulations.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿980.00
inventory 1g
10-20 days ฿2,460.00

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N-6-Methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]acetamide
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This compound is a key synthetic intermediate used in the production of dorzolamide, a sulfonamide-based carbonic anhydrase inhibitor. Dorzolamide is primarily employed as a topical ophthalmic agent for the treatment of glaucoma and ocular hypertension, where it reduces intraocular pressure by decreasing the formation of aqueous humor. The intermediate's structure, featuring a protected acetamide group at the 4-position of the thieno[2,3-b]thiopyran core and a sulfamoyl substituent, facilitates the enzym

This compound is a key synthetic intermediate used in the production of dorzolamide, a sulfonamide-based carbonic anhydrase inhibitor. Dorzolamide is primarily employed as a topical ophthalmic agent for the treatment of glaucoma and ocular hypertension, where it reduces intraocular pressure by decreasing the formation of aqueous humor. The intermediate's structure, featuring a protected acetamide group at the 4-position of the thieno[2,3-b]thiopyran core and a sulfamoyl substituent, facilitates the enzymatic inhibition mechanism in the final drug. It is not intended for direct therapeutic use but supports the manufacturing of specialized pharmaceutical formulations.

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