N-6-Methyl-7,7-dioxo-2-sulfamoyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl]acetamide
98%
science Other reagents with same CAS 147200-03-1
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description Product Description
This compound is a key synthetic intermediate used in the production of dorzolamide, a sulfonamide-based carbonic anhydrase inhibitor. Dorzolamide is primarily employed as a topical ophthalmic agent for the treatment of glaucoma and ocular hypertension, where it reduces intraocular pressure by decreasing the formation of aqueous humor. The intermediate's structure, featuring a protected acetamide group at the 4-position of the thieno[2,3-b]thiopyran core and a sulfamoyl substituent, facilitates the enzymatic inhibition mechanism in the final drug. It is not intended for direct therapeutic use but supports the manufacturing of specialized pharmaceutical formulations.
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