N-(4-sulfamoylphenyl)-2-(o-tolyl)quinoline-4-carboxamide
98%
Reagent
Code: #215646
CAS Number
544670-38-4
blur_circular Chemical Specifications
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Molecular Information
Weight
417.48 g/mol
Formula
C₂₃H₁₉N₃O₃S
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Storage & Handling
Density
1.363±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a potent inhibitor of carbonic anhydrase enzymes, particularly CA IX and CA XII, which are overexpressed in hypoxic tumor cells. This makes it valuable in cancer research, especially for developing targeted therapies against solid tumors such as breast, renal, and lung cancers. It shows promise in disrupting pH regulation in cancer cells, thereby inhibiting tumor growth and metastasis. Also investigated for its role in diagnostic imaging due to selective binding to tumor-associated carbonic anhydrase isoforms.
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