3-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonamide
97%
science Other reagents with same CAS 386273-25-2
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description Product Description
Used as a potent carbonic anhydrase inhibitor, this compound finds application in medicinal chemistry for the treatment of glaucoma by reducing intraocular pressure. It acts by inhibiting the carbonic anhydrase II and IX isoforms, which play roles in fluid production and tumor metabolism, respectively. Due to its sulfonamide group and aromatic structure, it also serves as a lead compound in the development of anticancer agents, particularly targeting hypoxic tumor cells where carbonic anhydrase IX is overexpressed. Additionally, its structural features make it useful in research settings for probing enzyme inhibition mechanisms and designing new isoform-selective inhibitors.
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