4-(5-(4-(Hydroxymethyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide

95%

Reagent Code: #191787
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CAS Number 170571-00-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 397.37 g/mol
Formula C₁₇H₁₄F₃N₃O₃S
badge Registry Numbers
MDL Number MFCD08063645
inventory_2 Storage & Handling
Storage Room temperature, light-proof, inert gas

description Product Description

Used primarily as a potent carbonic anhydrase inhibitor, this compound shows significant application in the treatment of glaucoma by reducing intraocular pressure. It acts by inhibiting carbonic anhydrase II and IX isoforms, which decreases aqueous humor production in the eye. Due to its sulfonamide group and strong binding affinity to the enzyme active site, it is also investigated for antitumor activity, particularly in hypoxic tumors where carbonic anhydrase IX is overexpressed. Additionally, it has been explored for use in anti-epileptic and anti-obesity research owing to central nervous system effects observed in preclinical studies. Its structural properties make it a valuable scaffold in medicinal chemistry for designing isoform-selective inhibitors.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿10,370.00
inventory 250mg
10-20 days ฿17,620.00
inventory 1g
10-20 days ฿47,550.00

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