Used as a stable isotope-labeled tracer in metabolic studies to track glycine metabolism in biological systems. Enables precise measurement of protein turnover, collagen synthesis, and one-carbon metabolism pathways. Commonly applied in mass spectrometry and nuclear magnetic resonance (NMR) research for accurate quantification of metabolic fluxes. Supports studies in amino acid metabolism, liver function, and cancer metabolism due to its non-radioactive and safe handling properties. Also utilized in the development and validation of analytical methods for biomedical and pharmaceutical research.