Used as a stable isotope-labeled internal standard in mass spectrometry and nuclear magnetic resonance (NMR) studies to accurately quantify uric acid metabolites in biological samples. Its isotopic enrichment with 13C and 15N allows for clear distinction from endogenous compounds, enhancing detection sensitivity and precision in metabolic research, particularly in studies related to purine metabolism, gout, and kidney function. Also employed in tracer experiments to track metabolic pathways without introducing chemical or biological interference.