Iron(II) D-gluconate dihydrate is widely used as a dietary supplement to treat or prevent iron deficiency anemia. It is particularly effective due to its high bioavailability and gentle effect on the stomach, making it suitable for individuals who experience gastrointestinal discomfort with other iron supplements. It is often included in multivitamin formulations, liquid supplements, and fortified foods. Additionally, it is used in pharmaceuticals for intravenous iron therapy in cases where oral supplementation is not feasible. Its mild taste and solubility also make it a preferred choice in pediatric and geriatric formulations. Beyond healthcare, it is utilized in food fortification to enhance the nutritional value of products like cereals, bread, and beverages.