Used in the production of sialic acid, N-Acetylmannosamine serves as a key metabolic precursor in biochemical pathways. It is widely applied in cell culture and biopharmaceutical manufacturing to enhance the sialylation of therapeutic proteins, particularly monoclonal antibodies, improving their stability, solubility, and in vivo efficacy. It is also employed in research on glycosylation disorders and as a supplement in media for the cultivation of certain cell types requiring high sialic acid content. Additionally, it has potential applications in glycoengineering to modulate immune responses and in the development of treatments for diseases involving defective glycosylation.