tert-Butyl (3-bromo-4-methylphenyl)carbamate

96%

Reagent Code: #153387
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CAS Number 515813-02-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 286.16 g/mol
Formula C₁₂H₁₆BrNO₂
badge Registry Numbers
MDL Number MFCD12913704
inventory_2 Storage & Handling
Storage 2-8°C, dry

description Product Description

Used as an intermediate in pharmaceutical synthesis, particularly in the production of kinase inhibitors and other bioactive molecules. The Boc-protected amine group on the 3-bromo-4-methylphenyl structure allows for selective reactions in multi-step organic syntheses, while the 3-bromo substituent facilitates nucleophilic substitutions or palladium-catalyzed cross-coupling reactions such as Suzuki or Buchwald-Hartwig to form carbon-carbon or carbon-nitrogen bonds. Commonly employed in the development of agrochemicals and medicinal compounds where controlled functionalization of aromatic amines is required. The tert-butyl carbamate (Boc) group provides stability under various reaction conditions and can be easily removed under mild acidic conditions when needed, making it valuable in peptide and heterocycle chemistry.

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Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿2,630.00
inventory 25g
10-20 days ฿11,400.00
inventory 100g
10-20 days ฿33,330.00

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