tert-Butyl (3-bromo-4-methylphenyl)carbamate
96%
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description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the production of kinase inhibitors and other bioactive molecules. The Boc-protected amine group on the 3-bromo-4-methylphenyl structure allows for selective reactions in multi-step organic syntheses, while the 3-bromo substituent facilitates nucleophilic substitutions or palladium-catalyzed cross-coupling reactions such as Suzuki or Buchwald-Hartwig to form carbon-carbon or carbon-nitrogen bonds. Commonly employed in the development of agrochemicals and medicinal compounds where controlled functionalization of aromatic amines is required. The tert-butyl carbamate (Boc) group provides stability under various reaction conditions and can be easily removed under mild acidic conditions when needed, making it valuable in peptide and heterocycle chemistry.
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