tert-Butyl (3-bromo-4-methylphenyl)carbamate

96%

Reagent Code: #153387
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CAS Number 515813-02-2

science Other reagents with same CAS 515813-02-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 286.16 g/mol
Formula C₁₂H₁₆BrNO₂
badge Registry Numbers
MDL Number MFCD12913704
inventory_2 Storage & Handling
Storage 2-8°C, dry

description Product Description

Used as an intermediate in pharmaceutical synthesis, particularly in the production of kinase inhibitors and other bioactive molecules. The Boc-protected amine group on the 3-bromo-4-methylphenyl structure allows for selective reactions in multi-step organic syntheses, while the 3-bromo substituent facilitates nucleophilic substitutions or palladium-catalyzed cross-coupling reactions such as Suzuki or Buchwald-Hartwig to form carbon-carbon or carbon-nitrogen bonds. Commonly employed in the development of agrochemicals and medicinal compounds where controlled functionalization of aromatic amines is required. The tert-butyl carbamate (Boc) group provides stability under various reaction conditions and can be easily removed under mild acidic conditions when needed, making it valuable in peptide and heterocycle chemistry.

Available Sizes & Pricing

Size Availability Unit Price Quantity
5g
10-20 days ฿2,630.00
25g
10-20 days ฿11,400.00
100g
10-20 days ฿33,330.00

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tert-Butyl (3-bromo-4-methylphenyl)carbamate
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Used as an intermediate in pharmaceutical synthesis, particularly in the production of kinase inhibitors and other bioactive molecules. The Boc-protected amine group on the 3-bromo-4-methylphenyl structure allows for selective reactions in multi-step organic syntheses, while the 3-bromo substituent facilitates nucleophilic substitutions or palladium-catalyzed cross-coupling reactions such as Suzuki or Buchwald-Hartwig to form carbon-carbon or carbon-nitrogen bonds. Commonly employed in the development of

Used as an intermediate in pharmaceutical synthesis, particularly in the production of kinase inhibitors and other bioactive molecules. The Boc-protected amine group on the 3-bromo-4-methylphenyl structure allows for selective reactions in multi-step organic syntheses, while the 3-bromo substituent facilitates nucleophilic substitutions or palladium-catalyzed cross-coupling reactions such as Suzuki or Buchwald-Hartwig to form carbon-carbon or carbon-nitrogen bonds. Commonly employed in the development of agrochemicals and medicinal compounds where controlled functionalization of aromatic amines is required. The tert-butyl carbamate (Boc) group provides stability under various reaction conditions and can be easily removed under mild acidic conditions when needed, making it valuable in peptide and heterocycle chemistry.

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