tert-Butyl (4-chloro-3-hydroxyphenyl)carbamate

97%

Reagent Code: #153293
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CAS Number 345893-27-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 243.69 g/mol
Formula C₁₁H₁₄ClNO₃
badge Registry Numbers
MDL Number MFCD09951954
inventory_2 Storage & Handling
Storage 2-8°C, dry

description Product Description

tert-Butyl (4-chloro-3-hydroxyphenyl)carbamate is a Boc-protected derivative of 4-chloro-3-hydroxyaniline, serving as a key intermediate in organic synthesis. It functions as an amine protecting group (Boc group) to prevent unwanted side reactions during multi-step syntheses, enabling precise control over reaction direction. The Boc group can be readily removed under mild acidic conditions, making it ideal for complex syntheses requiring high specificity, particularly for phenolic or aniline derivative structures. It is used in the synthesis of pharmaceutical compounds, especially drugs targeting central nervous system disorders, allowing selective modification for structure-activity relationship studies. Commonly employed in preparing beta-adrenergic receptor ligands and serotonin modulators. Additionally, it finds application in agrochemical production due to its stability and reactivity in coupling reactions.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿1,090.00
inventory 1g
10-20 days ฿4,350.00
inventory 5g
10-20 days ฿21,290.00

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