JWH 146 is primarily utilized in research settings to study its interactions with cannabinoid receptors, particularly CB1 and CB2. Its application is significant in understanding the pharmacological effects of synthetic cannabinoids on the endocannabinoid system. Researchers use it to explore potential therapeutic benefits, such as pain relief, anti-inflammatory properties, and neuroprotective effects. Additionally, it serves as a tool in investigating the structural and functional relationships of cannabinoid receptor agonists, aiding in the development of new pharmaceutical compounds. However, due to its psychoactive nature, its use is strictly limited to controlled laboratory environments.